Targeted binding of PEG-lipid modified polymer ultrasound contrast agents with tiered surface architecture
نویسندگان
چکیده
منابع مشابه
Targeted binding of PEG-lipid modified polymer ultrasound contrast agents with tiered surface architecture.
In order for site-directed polymer ultrasound contrast agents (UCAs) to provide acoustic enhancement at disease sites to distinguish normal tissue from diseased tissue, the surface of these agents must be functionalized with mixtures of grafted polymers. Here a combination of longer liganded polyethylene glycol (PEG)-lipids and shorter unliganded PEG-lipids were introduced into the oil phase of...
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ژورنال
عنوان ژورنال: Biotechnology and Bioengineering
سال: 2010
ISSN: 0006-3592,1097-0290
DOI: 10.1002/bit.22678